Opossums and Rabies: Why Anytime Contact Is Dangerous

When it comes to wildlife encounters in North America, opossums often stand out—not because of threat or danger, but due to a common misconception: their low risk of rabies and the surprising truth about their behavior. While many assume opossums are inherently dangerous, especially when encountered, the reality is that opossums rarely carry rabies and playing any role in contact with them is underlined by serious risk.

The Rabies Myth: Opossums Are Usually Safe

Understanding the Context

Contrary to widespread belief, opossums (Didelphis virginiana) are among the least likely wild mammals to carry rabies. Studies show that opossums have very low seroprevalence rates for the rabies virus—often below 0.1% in wild populations. Unlike many other mammals such as raccoons or bats in certain regions, opossums developed a natural resistance to rabies. Their unique immune system effectively suppresses the virus, making outbreaks rare in this species.

Despite this biological advantage, caution is still warranted. Opossums can contract rabies from infected animals through bites or scratches, though such cases are exceptionally uncommon. What makes opossums uniquely worrisome isn’t their disease status, but their susceptibility to injury, disease transmission, and dangerous interactions when stressed or cornered—often leading to unpredictable behavior.

Why Any Involuntary Contact Is Risky

Opossums are scavengers and survivors, often approaching human habitats in search of food or shelter. This natural tendency increases the likelihood of close contact—particularly when they hide under porches, garages, or near trash. However, contact feels harmless, but it poses significant dangers:

Key Insights

  • Bites and Scratches: Although less aggressive than other urban wildlife, opossums will defend themselves if cornered, leading to potential exposure to bite wounds or sharp claw injuries. Even minor wounds from an opossum’s teeth or claws can transmit bacteria or viruses through saliva or contaminated tissue.

  • Zoonotic Disease Risk: Opossums can carry parasites, fleas, and mites that pose indirect health risks. While rabies transmission is rare, exposure to saliva or feces increases risks of bacterial infections or zoonotic diseases, especially in children or immunocompromised individuals.

  • Aggressive Displays: When stressed or threatened, opossums may hiss, growl, or “play dead” (a confusing defense mechanism that looks like unconsciousness). This unpredictable behavior increases the risk of accidental bites if misinterpreted.

What You Should Do

Public awareness is key. If you encounter an opossum near your home:

Final Thoughts

  1. Do not approach or attempt to catch or handle it. Maintain safe distance.
    2. Secure garbage and food sources to avoid attracting opossums in the first place.
    3. Contact a licensed wildlife removal professional if the animal appears sick, aggressive, or trapped.
    4. Keep pets and livestock protected, as interactions with an injured or stressed opossum can lead to injury.

Final Thoughts

Opossums play a vital ecological role by controlling insect populations and scavenging waste. While they are not major carriers of rabies, any direct contact carries inherent risks that demand caution. Understanding their behavior, keeping a respectful distance, and consulting professionals when necessary ensures safety for both wildlife and people. Remember: admiring opossums safely from afar protects everyone—human or marsupial alike.


Topics: opossums, rabies prevention, wildlife safety, animal behavior, rabies myths, pet health, wildlife encounters
Keywords: opossum rabies, rabies in opossums, danger of contact with opossums, why opossum contact is dangerous, wildlife health, safe wildlife interaction, opossum behavior near homes

By recognizing these truths and acting responsibly, we reduce risks—keeping both people and wildlife safe in our shared neighborhoods.